Society, Energy, and Environment

What's New

October 2023

• Aluminum salts of inorganic phosphates was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• Aluminum metaphosphate was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• Monoaluminum phosphate was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• Phosphoric acid, aluminum salt (1:1) [aluminum phosphate] was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• Phosphoric acid, aluminum sodium salt (1:X:X) [sodium aluminum phosphate acidic (acidic SALP)] was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• Sodium aluminum phosphate (anhydrous) was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• Sodium aluminum phosphate (tetrahydrate) was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• Trialuminum sodium tetra decahydrogenoctaorthophosphate (dihydrate) was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• Triphosphoric acid, aluminum salt (1:1) [aluminum triphosphate] was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• 1-Phenyl-1-(2,4-dimethylphenyl)-ethane (PXE) was added to the database. The assessment has no toxicity values.
• The old paper for Methylcyclohexane was archived, and a new paper was added to the database. See attachment to the assessment's appendix for subchronic RfD and chronic RfC quantitative screening values.
• The old paper for Fluorene was archived, and a new paper was added to the database. A subchronic RfD was added.

April 2023

• The old paper for Isobutyl alcohol was archived, and a new paper was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfC quantitative screening values.
• The old paper for Perylene was archived, and a new paper was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD and RfC quantitative screening values.

December 2022

• A new paper for Sodium and Potassium Salts of Inorganinc Phosphates was added to the database. The chronic and subcrhonic RfD will apply to the following salts: Sodium Salts of Inorganic Phosphates, Potassium Salts of Inorganic Phosphates, Phosphoric acid, Polyphosphoric acid, Monosodium phosphate, Disodium phosphate, Trisodium phosphate, Sodium acid pyrophosphate, Tetrasodium pyrophosphate, Sodium tripolyphosphate, Sodium trimetaphosphate, Sodium polyphosphate, Sodium hexametaphosphate, Monopotassium phosphate, Dipotassium phosphate, Tripotassium phosphate, Tetrapotassium phosphate, and Potassium tripolyphosphate.

September 2022

• The old paper for Dibenzothiophene was archived, and a new paper was added to the database. The screening chronic RfD was dropped. See attachment to the assessment's appendix for subchronic RfD quantitative screening value.
• The noncarcinogenic inhalation values for cis-1,2-Dichloroethylene were archived, and a new paper was attached to the former paper for inhalation only. See attachment to the assessment's appendix for chronic and subchronic RfC quantitative screening values.
• The old paper for Total Petroleum Hydrocarbons Aliphatic Low was archived, and a new paper was added to the database. Chronic and subchronic RfDs and RfCs were added. See attachment to the assessment's appendix for inhalation unit risk quantitative screening value.
• The old paper for Total Petroleum Hydrocarbons Aliphatic Medium was archived, and a new paper was added to the database that maintains the same values.
• The old paper for Total Petroleum Hydrocarbons Aliphatic High was archived, and a new paper was added to the database that maintains the same values.
• The old paper for Total Petroleum Hydrocarbons Aromatic Low was archived, and a new paper was added to the database. The new paper drops all noncarcinogenic values and maintains the inhalation unit risk and oral slope factor.
• The old paper for Total Petroleum Hydrocarbons Aromatic Medium was archived, and a new paper was added to the database. Chronic and subchronic RfDs and RfCs were added.
• The old paper for Total Petroleum Hydrocarbons Aromatic High was archived, and a new paper was added to the database. Chronic and subchronic RfDs and RfCs, inhalation unit risk, and oral slope factor were added.

September 2021

• The old paper for Inorganinc Phosphates (and the 32 individual chemicals included) was archived. New papers were added to the database for Ammonium Salts of Inorganic Phosphates (including Monoammonium phosphate (MAP), Diammonium phosphate (DAP) and Ammonium polyphosphate (APP)) and Calcium Salts of Inorganic Phosphates (including Monocalcium phosphate (MCP), Dicalcium phosphate (DCP), Tricalcium phosphate (TCP), Calcium pyrophosphate (CPP), and Calcium hydroxide phosphate). See attachment to the assessment's appendix for screening subchronic RfD quantitative screening values.
• Benzo(e)pyrene was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD and RfC quantitative screening values.
• The old paper for 1-Bromo-2-chloroethane was archived, and a new paper was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD and RfC quantitative screening values.
• The old paper for trans-Crotonaldehyde was archived, and a new paper was added to the database. Chronic and Subchronic RfD assessments were added.
• The old paper for 3,5-Dinitroaniline was archived, and a new paper was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD and RfC quantitative screening values.
• The old paper for Pentaerythritol Tetranitrate (PETN) was archived, and a new paper was added to the database. Chronic and Subchronic RfD and oral slope factor assessments were added.
• The old paper for 2,3-Toluenediamine was archived, and a new paper was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• The old paper for 3,4-Toluenediamine was archived, and a new paper was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.

April 2021

• The old paper for Perfluorobutane Sulfonic Acid (PFBS) was archived, and a new paper was added to the database. Chronic and Subchronic RfD assessments were added.
• The old paper for Perfluorobutanesulfonate was archived, and a new paper was added to the database. Chronic and Subchronic RfD assessments were added.
• The old paper for Potassium Perfluorobutane Sulfonate was archived, and a new paper was added to the database. Chronic and Subchronic RfD assessments were added.

February 2021

• The old paper for trans-Crotonaldehyde was archived, and a new paper was added to the database. Chronic and Subchronic RfD assessments were added.

September 2020

• Glycidaldehye was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfC quantitative screening values.
• N,N,N',N''-Tetramethylphosphamide (TMPA) was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• Pentamethylphosphamide (PMPA) was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• The old paper for trans-1,2-Dichloroethylene was archived, and a new paper was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfC quantitative screening values.
• p-Phthalic Acid (Terephthalic Acid) was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• The old paper for Picric Acid was archived, and a new paper was added to the database. Subchronic RfD assessment was added. See attachment to the assessment's appendix for chronic RfD quantitative screening value.
• Ammonium Picrate was added to the database. Subchronic RfD assessment was added (based on exposure to Picric Acid). See attachment to the assessment's appendix for chronic RfD quantitative screening value.
• Vinyl Bromide was added to the database. Subchronic RfC and inhalation unit risk assessments were added.

May 2020

• 2-Amino-4,6-Dinitrotoluene was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• 4-Amino-2,6-Dinitrotoluene was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.

September 2019

• 2-Nitropropane was added to the database. See attachment to the assessment's appendix for subchronic RfD and RfC and inhalation unit risk quantitative screening values.
• Tetrachlorotoluene, p-alpha, alpha, alpha was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD and subchronic RfC quantitative screening values.

April 2019

• 2-Ethylhexanol was added to the database (also known as 2-Ethyl-1-hexanol). Chronic and Subchroninc RfD and RfC and Oral Slope Factor assessments were added.

March 2019

• Endosulfan Sulfate was revised. Chronic RfD assessment was added based on the RfD for Endosulfan, after applying molecular weight adjustment and appropriate stoichiometric calculations.

February 2019

• Styrene-Acrylonitrile (SAN) Trimer was modified to include both the Styrene-Acrylonitrile (SAN) Trimer (THNA isomer) and Styrene-Acrylonitrile (SAN) Trimer (THNP isomer). Both isomers have Chronic and Subchronic RfD assessments.

Septmeber 2018

• Lanthanum was added to the database. Chronic amd subchronic RfD assessments were added.
• Lanthanum Chloride, Anhydrous was added to the database. Chronic and subchronic RfD assessments were added based on the RfD for Lanthanum, after applying molecular weight adjustment and appropriate stoichiometric calculations.
• Lanthanum Chloride Heptahydrate was added to the database. Chronic and subchronic RfD assessments were added based on the RfD for Lanthanum, after applying molecular weight adjustment and appropriate stoichiometric calculations.
• Lanthanum Nitrate Hexahydrate was added to the database. Chronic and subchronic RfD assessments were added based on the RfD for Lanthanum, after applying molecular weight adjustment and appropriate stoichiometric calculations.
• Lanthanum Acetate Hydrate was added to the database. Chronic and subchronic RfD assessments were added based on the RfD for Lanthanum, after applying molecular weight adjustment and appropriate stoichiometric calculations.

August 2018 Updates

• The old paper for Lutetium was archived, and a new paper was added to the database. Subchronic RfD assessment was added.

July 2018 Updates

• Toxaphene, Technical was added to the database. Chronic and subchronic RfD assessments were added.
• Toxaphene, Weathered was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.

April 2018 Updates

• The old paper for Gadolinium was archived, and a new paper was added to the database. See attachment to the assessment's appendix for subchronic RfD quantitative screening value.

October 2017 Updates

• The old paper for p,p'-Dichlorodiphenyldichloroethane (p,p'-DDD) was archived, and a new paper was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• The old paper for p,p'-Dichlorodiphenyldichloroethylene (p,p'-DDE) was archived, and a new paper was added to the database. Subchronic RfD assessment was added. See attachment to the assessment's appendix for chronic RfD quantitative screening value.
• The old paper for 4-Methyl-2-pentanol was archived, and a new paper was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfC quantitative screening values.
• The old paper for tert-Butyl Formate was archived, and a new paper was added to the database. See attachment to the assessment's appendix for subchronic RfD quantitative screening value.
• The old paper for Lactonitrile was archived, and a new paper was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• The old paper for 1-Bromo-3-fluorobenzene was archived, and a new paper was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD and subchronic RfC quantitative screening values.
• The old paper for 1-Bromo-4-fluorobenzene was archived, and a new paper was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD and subchronic RfC quantitative screening values.
• The old paper for Diphenyl Ether was archived, and a new paper was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfC quantitative screening values.
• The old paper for p-Toluic Acid was archived, and a new paper was added to the database. Chronic and subchronic RfD assessments were added.

September 2017 Updates

• The old paper for n-Heptanal was archived, and a new paper was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfC quantitative screening values.
• The old paper for 2,2-Difluoropropane was archived, and a new paper was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfC quantitative screening values.

January 2017 Updates

• The old paper for p-Chlorobenzenesulfonic Acid was archived, and a new paper was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.

December 2016 Updates

• The Standard Operating Procedure (SOP) for PPRTV chemical nomination and selection, transmittal memo for the SOP, chemical nomination form, and candidate chemical selection and prioritation criteria form were added to the PPRTV home page.

September 2016 Updates

• The old paper for n-Heptane was archived, and a new paper was added to the database. Chronic and Subchronic RfC assessments were added. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• 2-Mercaptobenzothiazole was added to the database. Chronic and subchronic RfD and oral slope factor assessments were added.
• Rubidium was added to the database. See attachment to the assessment's appendix for subchronic RfD quantitative screening value.
• Rubidium Chloride was added to the database. See attachment to the assessment's appendix for subchronic RfD quantitative screening value.
• Rubidium Hydroxide was added to the database. See attachment to the assessment's appendix for subchronic RfD quantitative screening value.
• Rubidium Iodide was added to the database. See attachment to the assessment's appendix for subchronic RfD quantitative screening value.

August 2016 Updates

• The old paper for 3-Methylphenol was archived, and a new paper was added to the database. Subchronic RfD assessment was added.
• N,N-Dimethylaniline was added to the database. Subchronic RfD and oral slope factor assessments were added.
• p-Phenylenediamine was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.

January 2016 Updates

• The old paper for p-Chloronitrobenzene was archived, and a new paper was added to the database. Chronic and subchronic RfD and RfC and oral slope factor assessments were added.
• Benzaldehyde was added to the database. Subchronic RfD and oral slope factor assessments were added.

September 2015 Updates

• 2-Chlorobenzoic Acid was added to the database. Limitations in the data preclude development chronic or subchronic RfDs or RfCs.
• 1,1-Dichloropropene was added to the database. Limitations in the data preclude development chronic or subchronic RfDs or RfCs.
• 2,4,4-Trimethylpentene was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• The old paper for Picric Acid was archived, and a new paper was added to the database. Subchronic RfD assessment was added. See attachment to the assessment's appendix for chronic RfD quantitative screening value.
• Carbonyl Sulfide was added to the database. Chronic and subchronic RfC assessments were added.
• Diethylene Glycol Monomethyl Ether was added to the database. Chronic and subchronic RfD assessments were added.
• 1,1,1-Trifluoroethane was added to the database. Chronic and subchronic RfC assessments were added.
• Lewisite was added to the database. Chronic and subchronic RfD assessments were added.
• Tungsten was added to the database. Chronic and subchronic RfD assessments were added.
• Sodium Tungstate was added to the database. Chronic and subchronic RfD assessments were added.
• Sodium Tungstate Dihydrate was added to the database. Chronic and subchronic RfD assessments were added.

August 2015 Updates

• 1-Chlorooctadecane was added to the database. Limitations in the data preclude development chronic or subchronic RfDs or RfCs.
• Diundecyl phthalate was added to the database. Subchronic RfD assessment was added.

September 2014 Updates

• Ethyl Acrylate was added to the database. Chronic RfD and RfC and subchronic RfC assessments were added. See attachment to the assessment's appendix for subchronic RfD quantitative screening value.
• Triethylene Glycol was added to the database. Chronic and subchronic RfD assessments were added.
• Propylene Glycol Monoethyl ether, alpha isomer was added to the database. Limitations in the data preclude development chronic or subchronic RfDs or RfCs.
• Propylene Glycol Monoethyl ether, beta isomer was added to the database. Limitations in the data preclude development chronic or subchronic RfDs or RfCs.
• Isopropanol was added to the database. Chronic and subchronic RfD and RfC assessments were added.
• The old paper for 2-Methylphenol was archived, and a new paper was added to the database. Subchronic RfD assessment was added.

August 2014 Updates

• Styrene-Acrylonitrile (SAN) Trimer was added to the database. Chronic and subchronic RfD assessments were added.

July 2014 Updates

• The old paper for 1,3-Dibromobenzene with no values was archived, and a new paper was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• Perfluorobutane Sulfonate was added to the database. Chronic and subchronic RfD assessments were added.
• Potassium Perfluorobutane Sulfonate was added to the database. Chronic and subchronic RfD assessments were added.

April 2014 Updates

• The chronic RfC assessment for Dichloroethylene, trans-1,2- was archived. See this memo for an explanation.

March 2014 Updates

• Azodicarbonamide was added to the database. Chronic and subchronic RfD and RfC assessments were added.
• Guanidine Chloride was added to the database. Chronic and subchronic RfD assessments were added.
• Guanidine was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• The old paper for Guanidine Nitrate was archived and a new paper was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.

February 2014 Updates

• Aroclor 5460 was added to the database. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.

January 2014 Updates

• The old paper for Dicyclopentadiene was archived and a new paper was added to the database. Chronic and Subchronic RfD assessments and screening chronic and subchronic RfC assessments were added.

September 2013 Updates

• The old paper for 1,2,4,5-Tetrachlorobenzene was archived and a new paper was added to the database. Subchronic RfD assessment was added.

August 2013 Updates

• The oral slope factor for 1,1,-Biphenyl was removed. Please see the IRIS summary.
• 3,4-Dichlorobenzotrifluoride was added to the database. See attachment to the assessment's appendix for subchronic RfD quantitative screening value.
• The old paper for Trinitrophenylmethylnitramine (Tetryl) was archived and a new paper was added to the database. Chronic and Subchronic RfD assessments were added
• The old paper for Endosulfan Sulfate was archived and a new paper was added to the database. See attachment to the assessment's appendix for subchronic RfD quantitative screening value.
• 1,1,2,2-Tetrachloroethane was removed from the PPRTV as IRIS values should be used instead. Please see the IRIS Summary for 1,1,2,2-Tetrachloroethane.

July 2013 Updates

• The old paper for Nitromethane was archived and a new paper was added to the database. Chronic and subchronic RfC and inhalation unit risk assessments were added.
• The old paper for Dibenzothiophene was archived and a new paper was added to the database. See attachment to the assessment's appendix for chronic RfD quantitative screening value.

June 2013 Updates

• The old paper for 2-Ethoxyethanol was archived and a new paper was added to the database. Chronic and subchronic RfD and subchronic RfC assessments were was added.
• 3,3'-Dimethoxybenzidine was added to the database. Oral slope factor was added. See attachment to the assessment's appendix for subchronic RfD quantitative screening value.
• Butylated hydroxytoluene was added to the database. Chronic and subchronic RfD and Oral slope factor assessments were added.

May 2013 Updates

• Ethyl Acetate was added to the database. Chronic and subchronic RfD and RfC assessments were added.
• tert-Amyl Alcohol was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Oral slope factor and inhalation unit risk values were updated for Total Petroleum Hydrocarbons (aromatic low) to reflect the more conservative value in the range provided (and that match the values for Benzene, the representative chemical for that hydrocarbon class)

April 2013 Updates

• 2,2-Difluoropropane was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC.
• The old paper for 2,6-Dinitrotoluene was archived and a new paper was added to the database. Oral slope factor was added. See attachment to the assessment's appendix for chronic and subchronic RfD quantitative screening values.
• Dinitrotoluene, Technical grade was added to the database. See attachment to the assessment's appendix for quantitative screening values.

February 2013 Updates

• Diisopropyl Methylphosphonate was added to the database. Chronic and subchronic RfD assessments were added.

January 2013 Updates

• A revised paper for Toluene-2-5-diamine and compounds was added to the database. See attachment to the assessment's appendix for quantitative screening values for 1,4-Benzenediamine-2-methyl sulfate; 2-Methylbenzene-1,4-diamine sulfate; Toluene-2,5-diamine free-base; Toluene-2,5-diamine dihydrochloride; and Toluene-2,5-diamine monohydrochloride.
• The old paper for Methylcyclohexane was archived and a new paper was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC.

December 2012 Updates

• Zirconium (Soluble Compounds) was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• The old paper for Fluoranthene was archived and a new paper was added to the database. Subchronic RfD assessment was added.
• The old paper for D-n-Octyl Phthalate was archived and a new paper was added to the database. Chronic and subchronic RfD assessments were added.
• Cyanogen Bromide was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Thiocyanic acid was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Chloromethane was added to the database. Subchronic RfC assessment was added.
• Cyclohexene was added to the database. Chronic and subchronic RfD assessments were added. See attachment to the assessment's appendix for quantitative screening values.
• o-Toluidine was added to the database. Oral slope factor assessments were added. See attachment to the assessment's appendix for quantitative screening values.

November 2012 Updates

• 1,1,2-Trichloropropane was added to the database. Chronic and subchronic RfD assessments were added.
• Tris(1-chloro-2-propyl)phosphate was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• The old paper for sec-Butylbenzene was archived and a new paper was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• The old paper for tert-Butylbenzene was archived and a new paper was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• 2-Chloroethanol was added to the database. Chronic and subchronic RfD assessments were added.
• The old paper for Methyacrylonitrile was archived and a new paper was added to the database. Subchronic RfD and Chronic and Subchronic RfC assessments were added with the new paper.
• Triacetin was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• A new paper for p-Toluidine was added to the database. Oral slope factor assessment was added. See attachment to the assessment's appendix for RfD quantitative screening values. The old paper was archived.
• Methyl Acrylate was added to the database. Chronic and subchronic RfC assessments were added.
• Boron Trichloride was added to the database. Chronic and subchronic RfD and RfC assessments were added.
• Nitrofen was added to the database. Chronic and subchronic RfD and oral slope factor assessments were added.
• The old paper for Ethylene Cyanohydrin was archived and a new paper was added to the database. Chronic and subchronic RfD assessments were added.

October 2012 Updates

• A new paper for Acetone Cyanohydrin was added to the database. See attachment to the assessment's appendix for quantitative screening values. The old paper was archived.

September 2012 Updates

• Thallium Soluble Salts was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Thallium Acetate was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Thallium Carbonate was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Thallium Chloride was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Thallium Nitrate was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Thallium Sulfate was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Total Petroleum Hydrocarbons was broken into 6 hydrocarbon classes (aliphatic high, aliphatic medium, aliphatic low, armotic high, aromatic medium, and aromatic low)

August 2012 Updates

• Dinitrosopentamethylenetetramine, N,N- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• The PPRTV Derivation Support Documents page was revised to allow documents to be sorted by chemical, CAS number, or last updated date.

July 2012 Updates

• Endrin Ketone was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

June 2012 Updates

• 2,2-Dichloropropane was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Tridymite was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

April 2012 Updates

• Iron Sulfide was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

March 2012 Updates

• tert-Butyl Formate was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Hexamethylphosphoramide was added to the database. RfD assessment was added.
• The old paper for Diethylphosphorodithioate was archived and a new paper was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• 3-nitro-4-Chlorobenzotrifluoride was added to the database. See attachment to the assessment's appendix for quantitative screening values.

January 2012 Updates

• Sulfolane was added to the database. RfD and RfC assessments were added.

September 2011 Updates

• 1,3-Dibromobenzene was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• 3-(NN-dimethylamino) Proprionitrile was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC.

August 2011 Updates

• 2-Nitrodiphenylamine was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Dicyclohexylamine was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

July 2011 Updates

• Tris(3-chloro-1-propyl)phosphate was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• The old paper for p-Isopropyltoluene was archived and a new paper was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

June 2011 Updates

• Acetophenone was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• 3-Amino-4-chlorobenzotriofluoride was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• n-Heptanal was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

May 2011 Updates

• Guanidine Nitrate was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• n,n-Dimethylcyclohexylamine was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Pentamethyl Dipropylenetriamine was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• 1,2,3-Trimethyl-4-propenylnaphthalene was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• The old paper for Diphenylamine was archived and a new paper was added to the database. See attachment to the assessment's appendix for quantitative screening values.

April 2011 Updates

• n-Mehylcyclohexylamine was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• The old paper for Acenaphthene was archived and a new paper was added to the database. An RfD assessment was added
• Benzotrichloride was added to the database. RfD and RfC assessments were added.
• The old paper for Diisopropyl Ether was archived and a new paper was added to the database. An RfC assessment was added
• 1,1-Biphenyl was added to the database. RfD and RfC assessments and an oral slope factor were added.
• Benzenethiol was added to the database. An RfD assessment was added
• 2,3-Benzofluorene was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• 2-Methoxyethanol Acetate was added to the database. RfD and RfC assessments were added.
• The old paper for 2-Methoxyethanol was archived and a new paper was added to the database. RfD and RfC assessments were added
• Phenothiazine was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• 1,1,2-Trichloroethane was added to the database. RfD and RfC assessments were added.

March 2011 Updates

• 1-Bromo-3-fluorobenzene was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• 2-Methyl-5-nitroaniline was added to the database. RfD and oral slope factor assessments were added.
• Bis(2-chloro-1methylethyl)ether was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• 2,4-Dimethylaniline was added to the database. RfD and oral slope factor assessments were added.
• 1-Bromo-4-ethylbenzene was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• 2-Bromopyridine was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• 3-Bromoacetophenone was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Fluorobenzene was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• n-Methyl dicyclohexylamine was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Inorganic Phosphates were added to the database. See the paper for RfD assessments for Aluminum metaphosphate, Ammonium polyphosphate, Calcium pyrophosphate, Diammonium phosphate, Dicalcium phosphate, Dimagnesium phosphate, Dipotassium phosphate, Disodium phosphate, Inorganic Phosphates, Monoaluminum phosphate, Monoammonium phosphate, Monocalcium phosphate, Monomagnesium phosphate, Monopotassium phosphate, Monosodium phosphate, Orthophosphoric acid, Phosphoric Acid, Polyphosphoric acid, Potassium tripolyphosphate, Sodium acid pyrophosphate, Sodium aluminum phosphate (acidic), Sodium aluminum phosphate (anhydrous), Sodium aluminum phosphate (tetrahydrate), Sodium hexametaphosphate, Sodium polyphosphate, Sodium trimetaphosphate, Sodium tripolyphosphate, Tetrapotassium phosphate, Tetrasodium pyrophosphate, Trialuminum sodium tetra decahydrogenoctaorthophosphate (dihydrate), Tricalcium phosphate, Trimagnesium phosphate, Tripotassium phosphate, and Trisodium phosphate

February 2011 Updates

• Anthraquinone was added to the database. RfD and oral slope factor assessments were added.
• The old paper for cis-1,2-Dichloroethylene was archived and a new paper was added to the database. An RfD assessment was added

October 2010 Updates

• Thallium and Compounds was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• The old paper for Acrylic Acid was archived and a new paper was added to the database. RfD and RfC assessments were added
• The old paper for 1,2-Dichloroethane was archived and a new paper was added to the database. RfD and RfC assessments were added
• The old paper for Formic Acid was archived and a new paper was added to the database. RfD and RfC assessments were added

September 2010 Updates

• 4-Chloro-2-methylaniline was added to the database. RfD and oral slope factor assessments were added.
• o-Chlorotoluene was added to the database. RfD and oral slope factor assessments were added.
• The old paper for Hexachlorobenzene was archived and a new paper was added to the database. An RfD assessment was added
• Pentaerythritol tetranitrate (PETN) was added to the database. RfD and oral slope factor assessments were added.
• Trimethyl phosphate was added to the database. RfD and oral slope factor assessments were added.
• Coronene was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Cyclohexane was added to the database. An RfC assessment was added.
• The old paper for Methyl Hydrazine was archived and a new paper was added to the database. RfD, RfC and oral slope factor assessments were added
• 4-Methylphenol was added to the database. An RfD assessment was added.
• 2,4,6-Trichloroaniline was added to the database. RfD and oral slope factor assessments were added.
• Methyl Acetate was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Ethyl Methacylate was added to the database. RfD and RfC assessments were added.
• Stearyl Acetate was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Titanium was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• 2-Methyl-1,4-benzenediamine dihydrochloride was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• 2-Methylbenzene-1,4-diamine monohydrochloride was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Octahydrotrimethylmethylethylphenanthrenol was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Tricaine Methanesulfonate was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• The old paper for Cyclohexanone was archived and a new paper was added to the database. RfD and RfC assessments were added
• The old paper for n-Butylbenzene was archived and a new paper was added to the database. An RfD assessment was added
• Ethoxyethanol Acetate was added to the database. RfD and RfC assessments were added.

June 2010 Updates

• 1,2,3-Trimethylbenzene was added to the database. An RfC assessment was added.
• The old paper for Crotonaldehyde was archived and a new paper was added to the database. An RfD assessment was added

April 2010 updates

• The old paper for 4,6-Dinitro-o-cresol was archived and a new paper was added to the database. An RfD assessment was added

September 2009 Updates

• The old paper for Benzyl Alcohol was archived and a new paper was added to the database. An RfD assessment was added.
• Bromobenzene was archived and removed from the database.
• The old paper for Chloro-m-cresol, p- was archived and a new paper was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Complex Mixtures of Aliphatic and Aromatic Hydrocarbons were added to the database. See the paper for values.
• Dibromochloromethane was added to the database. An RfD assessment was added.
• The old paper for Dimethylhydrazine, 1,1- was archived and a new paper was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• The old paper for Endosulfan was archived and a new paper was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Hexane, N- was added to the database. An RfD assessment was added
• The old paper for Commercial Hexane was archived and a new paper was added to the database. An RfD assessment was added
• The old paper for Iodomethane was archived and a new paper was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• The old paper for Methylene Bromide was archived and a new paper was added to the database. RfD and RfC assessments were added
• The old paper for Midrange Aliphatic Hydrocarbon Streams was archived and a new paper was added to the database. RfD, RfC, and inhalation unit risk assessments were added
• The old paper for Naphtha, High Flash Aromatic (HFAN) was archived and a new paper was added to the database. RfD and RfC assessments were added
• Naphthylamine, 2- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• The old paper for Tetrachloroethane, 1,1,1,2- was archived and a new paper was added to the database. An RfD assessment was added
• The old paper for Tris(2-Chloroethyl)Phosphate was archived and a new paper was added to the database. RfD and oral slope factor assessments were added
• Vanadium was added to the database. An RfD assessment was added
• Xylene, mixture was added to the database. RfD and RfC assessments were added
• The old paper for Allyl Alcohol was archived and a new paper was added to the database. RfD and RfC assessments were added
• Benzene was added to the database. RfD and RfC assessments were added
• The old paper for Diphenol Sulfone was archived and a new paper was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• The old paper for Toluene was archived and a new paper was added to the database. RfD and RfC assessments were added
• White Mineral Oil was added to the database. An RfD assessment was added
• The old paper for Dichlorobenzophenone, 4,4'- was archived and a new paper was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• The old paper for Diethylene Glycol Monobutyl Ether was archived and a new paper was added to the database. RfD and RfC assessments were added
• Nonane, n- was added to the database. RfD and RfC assessments were added
• The old paper for Sulfonylbis(4-chlorobenzene), 1,1'- was archived and a new paper was added to the database. An RfD assessment was added
• Decane, n- was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Neodymium Chloride was added to the database. An RfD assessment was added
• Praseodymium Chloride was added to the database. An RfD assessment was added
• Saramium Chloride was added to the database. An RfD assessment was added
• Saramium Nitrate was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Bromodichloromethane was added to the database. RfD and RfC assessments were added
• The old paper for Methylcyclopentane was archived and a new paper was added to the database. An RfD assessment was added
• The old paper for Picramic Acid was archived and a new paper was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• The old paper for Trichlorofluoromethane was archived and a new paper was added to the database. An RfD assessment was added
• The old paper for Ethylbenzene was archived and a new paper was added to the database. RfD and RfC assessments were added
• The old paper for Nitroaniline, 2- was archived and a new paper was added to the database. RfD and RfC assessments were added
• Nitrosopyrrolidine was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Trichlorobenzene, 1,2,3- was added to the database. An RfD assessment was added
• Bromochloromethane was added to the database. An RfC assessment was added
• The old paper for Diphenyl-1,4-benzenediamine, N,N'- was archived and a new paper was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Hydrazine was added to the database. RfD and RfC assessments were added
• The old paper for Hydroquinone was archived and a new paper was added to the database. RfD and oral slope factor assessments were added
• Nitrocellulose was added to the database. An RfD assessment was added
• Pentane, n- was added to the database. An RfC assessment was added
• Phenyl Isothiocyanate was added to the database. An RfD assessment was added
• The old paper for Chloronaphthalene, 2- was archived and a new paper was added to the database. An RfD assessment was added
• Tribromophenol, 2,4,6- was added to the database. An RfD assessment was added

August 2009 Updates

• The old paper for Trichloropropene, 1,2,3- was archived and a new paper was added to the database. RfD and RfC assessments were added

July 2009 Updates

• Selenourea was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• The old paper for Chlorobenzene sulfonic acid, p- was archived and a new paper was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

June 2009 Updates

• The old paper for Chloronitrobenzene, o- was archived and a new paper was added to the database. RfD, RfC, and oral slope factor assessments were added
• The old paper for Nitrotoluene, m- was archived and a new paper was added to the database. An RfD assessment was added
• Thiodiglycol was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• The old paper for Trichlorobenzene, 1,2,4- was archived and a new paper was added to the database. RfD and RfC assessments were added
• Anthracene was added to the database. An RfD assessment was added

April 2009 Updates

• The old paper for Trimethylbenzene, 1,3,5- was archived and a new paper was added to the database. RfD and RfC, and oral slope factor assessments were added

March 2009 Updates

• The old paper for Phenanthrene was archived and a new paper was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

February 2009 Updates

• The old paper for Nitroaniline, 3- was archived and a new paper was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Butyl alcohol, sec- was added to the database. RfD and RfC assessments were added
• Propylbenzene, n- was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• The old paper for Nitroaniline, 4- was archived and a new paper was added to the database. RfD, RfC, and oral slope factor assessments were added

January 2009 Updates

• Ethyl Ether was added to the database. RfD and RfC assessments were added
• Nitroguanidine was added to the database. An RfD assessment was added

October 2008 Updates

• Dichloro-2-butene, 1,4- was added to the database. An inhalation unit risk assessment was added
• Dichloro-2-butene, cis-1,4- was added to the database. An inhalation unit risk assessment was added
• Dichloro-2-butene, trans-1,4- was added to the database. An inhalation unit risk assessment was added

September 2008 Updates

• The old paper for Chloroaniline, p- was archived and a new paper was added to the database. RfD and oral slope factor assessments were added

August 2008 Updates

• The old paper for Dimethylbenzidine, 3,3'- was archived and a new paper was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• The old paper for Cobalt was archived and a new paper was added to the database. RfD, RfC, and inhalation unit risk assessments were added
• The old paper for Nitrotoluene, o- was archived and a new paper was added to the database. RfD and oral slope factor assessments were added
• The old paper for Tetrachloroethane, 1,1,2,2- was archived and a new paper was added to the database. An RfD assessment was added
• Antimony Trioxide was added to the database. RfD and RfC assessments were added

July 2008 Updates

• Acenaphthylene was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• The old paper for Antimony was archived and a new paper was added to the database. An RfD assessment was added
• Soluble Antimony Compounds (Antimony Potassium Tartrate) was added to the database. An RfD assessment was added
• Soluble Antimony Compounds (Antimony Trichloride) was added to the database. An RfD assessment was added
• Hexachlorocyclohexane, Delta- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Carbazole was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Benzyl Chloride was added to the database. RfD and RfC assessments were added
• Endrin Aldehyde was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Lithium was added to the database. An RfD assessment was added

May 2008 Updates

• Tetramethylcyclohexane was added to the database. An RfD assessment was added

April 2008 Updates

• Vanadium Pentoxide was added to the database. RfC and inhalation unit risk assessments were added
• Chloronitrobenzene, p- was added to the database. RfD, RfC, and oral slope factor assessments were added

March 2008 Updates

• The old paper for Propylene Glycol was archived and a new paper was added to the database. An RfD assessment was added
• The old paper for Diethylformamide was archived and a new paper was added to the database. An RfD assessment was added

January 2008 Updates

• Methylnaphthalene, 1- was added to the database. RfD and oral slope factor assessments were added

September 2007 Updates

• The old paper for Nitrotoluene, p- was archived and a new paper was added to the database. RfD and oral slope factor assessments were added
• Pentachloroethane was added to the database. An oral slope factor assessment was added
• Dimethylformamide was added to the database. RfD and RfC assessments were added
• Promethium was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Dimethylphthalate was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Dinitrophenol, 2,4- was added to the database. An RfD assessment was added
• Phosphorus Pentoxide was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Bromo-2-chloroethane, 1- was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Nitrophenol, 2- was added to the database. An RfC assessment was added
• The old paper for Nitrosodiphenylamine, N- was archive and a new paper was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Methylnaphthalene, 2- was added to the database. An RfD assessment was added
• Gadolinium was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Pyrene was added to the database. An RfD assessment was added
• The old paper for Praseodymium was archived. No new paper is available.

August 2007 Updates

• Tetrahydrothiophene was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• DDD, o,p'- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• The old paper for DDD, p,p'- was archived and a new paper was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Tetrachlorobenzene, 1,2,4,5- was added to the database. An RfD assessment was added
• Thiophene was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

July 2007 Updates

• Endosulfan Sulfate was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Dichlorophenol, 2,4- was added to the database. An RfD assessment was added
• Perylene was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Trichlorophenol, 2,4,5- was added to the database. An RfD assessment was added
• DDE, p,p'- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Chloroethane was added to the database. RfD and RfC assessments were added
• Hexachlorobutadiene was added to the database. An RfD assessment was added
• Chlorophenol, 2- was added to the database. An RfD assessment was added

June 2007 Updates

• Dimethylphenol, 2,4- was added to the database. An RfD assessment was added
• Benz(a)anthracene was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Chlorobenzoic Acid, p- was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Nitrosodimethylamine, N- was added to the database. RfD and RfC assessments were added
• The old paper for Dibenzofuran was archived and a new paper was added to the database. An RfD assessment was added
• The old paper for Trimethylbenzene, 1,2,4- was archived and a new paper was added to the database. An RfC assessment was added
• Bromomethane was added to the database. RfD and RfC assessments were added

May 2007 Updates

• Lutetium was added to the database. An RfD assessment was added
• Aniline was added to the database. An RfD assessment was added
• Chlorobenzotrifluoride, 4- was added to the database. RfD and RfC assessments were added
• The old paper for Triphenylphosphine Oxide was archived and a new paper was added to the database. An RfD assessment was added
• Propyl Alcohol, n- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

April 2007 Updates

• Malononitrile was added to the database. An RfD assessment was added

March 2007 Updates

• Trichlorophenol, 2,4,6- was added to the database. An RfD assessment was added

October 2006 Updates

• Aminophenol, m- was added to the database. An RfD assessment was added
• Aluminum was added to the database. RfD and RfC assessments were added
• Bifenox was added to the database. An RfD assessment was added
• Chlorobenzene was added to the database. RfD and RfC assessments were added
• Dimethyl Methylphosphonate was added to the database. RfD and oral slope factor assessments were added

September 2006 Updates

• Dichloroethane, 1,1- was added to the database. An RfD assessment was added
• Bis(2-chloroethoxy)methane was added to the database. An RfD assessment was added
• Chloro-6-fluorophenol, 2- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Hexanedioic Acid was added to the database. An RfD assessment was added
• Iron and Compounds was added to the database. An RfD assessment was added

August 2006 Updates

• Nitroglycerin was added to the database. RfD and oral slope factor assessments were added
• Epichlorohydrin was added to the database. RfD and RfC assessments were added
• Ethylene Diamine was added to the database. An RfD assessment was added
• Dibromo-3-Chloropropane, 1,2- was added to the database. RfD, RfC, oral slope factor, and inhalation unit risk assessments were added
• Methylenebis(2-Chloroaniline), 4,4' was added to the database. RfD and oral slope factor assessments were added

July 2006 Updates

• Dinitrobenzene, 1,2- was added to the database. An RfD assessment was added

June 2006 Updates

• Dinitrobenzene, 1,4- was added to the database. An RfD assessment was added

March 2006 Updates

• The old paper for Thiocyanates was archived and a new paper was added to the database. An RfD assessment was added
• Butyltin Compounds, Di- was added to the database. An RfD assessment was added
• Butyltin Compounds, Mono- was added to the database. An RfC assessment was added
• Butyltin Compounds, Tri- was added to the database. An RfD assessment was added
• Dichloroethylene, trans-1,2- was added to the database. An RfC assessment was added
• Dichloropropane, 1,3- was added to the database. An RfD assessment was added

Feburary 2006 Updates

• Aminopyridine, 4- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

November 2005 Updates

• Prussian Blue was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

October 2005 Updates

• Adiponitrile was added to the database. An RfC assessment was added
• Chlorobutane, 1- was added to the database. An RfD assessment was added

September 2005 Updates

• Trichlorotoluene, alpha-2,6- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Trichlorotoluene, 2,3,6- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

August 2005 Updates

• Phthalic Acid, o- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Chloropropane, 2- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Aminophenol, p- was added to the database. An RfD assessment was added
• Toluenediamine, 2,6- was added to the database. An RfD assessment was added
• Toluenediamine, 3,4- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Methylaniline, N- was added to the database. An RfD assessment was added

July 2005 Updates

• Aminophenol, o- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• The old paper for Cerium, Stable was archived. No new paper is available.

June 2005 Updates

• Toluenediamine, 2,3- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Hexadecanoic Acid was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

May 2005 Updates

• Amino-2,6-Dinitrotoluene, 4- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Amino-4,6-Dinitrotoluene, 2- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Methyl-2-Pentanol, 4- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Lactonitrile was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

April 2005 Updates

• Chlorobutane, 2- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Phthalic Acid, m- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Bromoform was added to the database. An RfD assessment was added

March 2005 Updates

• Benzoic Acid was added to the database. RfD and RfC assessments were added
• Nitromethane was added to the database. RfC and inhalation unit risk assessments were added
• Anilinobenzothiazole was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Dicyclopentadiene was added to the database. RfD and RfC assessments were added
• Aldrin was added to the database. An RfD assessment was added
• Dimethyl Sulfide was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

February 2005 Updates

• Ammonia was added to the database. An RfC assessment was added

January 2005 Updates

• Ethylene Cyanohydrin was added to the database. An RfD assessment was added

December 2004 Updates

• The old paper for Chlorotoluene, p- was archived and a new paper was added to the database. An RfD assessment was added
• Dimethylphenethylamine was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Octadecanoic Acid was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Alizarin Red Compounds was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Dibenzothiophene was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Fluorobiphenol, 2- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Methyl Mercaptan was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Dimethylmercury was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

November 2004 Updates

• Chloroacetic Acid was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Benzothiazole was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Bromofluorobenzene, p- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Dinitroaniline, 3,5- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Fluorophenol, 2- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Heptane, n- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Nicotinonitrile was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Trinitrophenylmethylnitramine (Tetryl) was added to the database. An RfD assessment was added

November 2003 Updates

• Dichloropropane, 1,2- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

August 2003 Updates

• DDT, o,p'- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• The old paper for Chlordecone/(Kepone) was archived. No new paper is available.

November 2002 Updates

• The old paper for Ceric Oxide was archived. No new paper is available.

October 2002 Updates

• Butyl benzyl phthalate was added to the database. An oral slope factor assessment was added

September 2002 Updates

• Picric Acid was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Mercuric Sulfide was added to the database. An RfD assessment was added
• Nitrophenol, p- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• The old paper for Methyl Phosphonic Acid was archived and a new paper was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• The old paper for Tributyl Phosphate was archived and a new paper was added to the database. RfD and oral slope factor assessments were added
• The old paper for Diethylene Glycol Monoethyl Ether was archived and a new paper was added to the database. RfD and RfC assessments were added
• Tris(2-ethylhexyl)Phosphate was added to the database. RfD and oral slope factor assessments were added
• The old paper for Cacodylic Acid was archived. No new paper is available.
• The old paper for Tungsten was archived. No new paper is available.

August 2002 Updates

• The old paper for Arsenic, Inorganic was archived. No new paper is available.

May 2002 Updates

• The old paper for Dichlorodifluoromethane was archived and a new paper was added to the database. RfD and RfC assessments were added
• Dichloroethylene, 1,2- (mixed isomers) was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Dinoseb was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Disulfoton was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Endrin was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Fluorene was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Isobutanol (Isobutyl Alcohol) was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

April 2002 Updates

• Acrolein was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Benzo(b)fluoranthene was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

January 2002 Updates

• Ethoxyethanol, 2- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Ideno[1,2,3-cd]pyrene was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Methylphenol, 2- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Methylphenol, 3- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

November 2001 Updates

• Benzo(k)fluoranthene was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• Bromodiphenyl Ether, 4- was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.
• The old paper forChloroacetaldehyde, 2 was archived and a new paper was added to the database. See attachment to the assessment's appendix for quantitative screening values.
• Chrysene was added to the database. Limitations in the data preclude development of a chronic or subchronic RfD or RfC or a WOE descriptor.

August 1999 Updates

• The old paper for Trichloroethane, 1,1,1- was archived. No new paper is available.

June 1999 Updates

• The old paper for Carbon Tetrachloride was archived. No new paper is available.
• The old paper for Chlorine was archived. No new paper is available.

June 1998 Updates

• The old paper for Acetone was archived. No new paper is available.
• The old paper for Cadmium (diet) was archived. No new paper is available.